Endocrine Abstracts

Up-to-date dual-energy X-ray absorptiometry (DXA) offers an insight into body composition (fat and lean mass) in different body regions.Objectives: To measure the regional fat and lean mass in women of different age and to describe age-related changes.Material and Methods: One hundred and twenty women referred for DXA participated in the whole body (WB) study – age range was 20–75 yrs. They were subdivided in three age gr...

The identification of type 2 diabetes patients at particularly high risk for cardiovascular events might be facilitated by the use of specific risk calculators or by measurements of serum biomarkers.Objectives: To correlate the levels of cardiovascular biomarkers – assymetric dymethylarginine (ADMA), endothelin 1 (ET-1), N-terminal brain natriuretic pro-peptide (NT-proBNP) and placental growth factor (PIGF-1), with calculated cardiovascular risks us...

Aims: To explore the correlations of BMI, waist circumference (WC), waist–to–height ratio (WHtR), waist–to–hip ratio (WHR) and body composition with levels of assymetric dymethylarginine (ADMA), endothelin 1(ET–1), N–terminal brain natriuretic pro–peptide (NT–proBNP), uric acid and calculated cardiovascular risks.Methods: 102 women and 67 men with type 2 diabetes on oral antidiabetic drugs participated. Ser...

Until recently primary aldosteronism /PA/ was thought to be rare, accounting for no more than 0.05–2% of the hypertensive patients. Studies published in the last decade demonstrate that primary hyperaldosteronism is a much more common cause of secondary hypertension than was previously thought, accounting for as many as 5% to 25% of hypertensives in some series. For the present, there are no data concerning the prevalence of PA in Bulgaria which determined the realization...

Primary hyperparathyroidism (PHPT) is being more and more frequently diagnosed.Objectiveto describe the clinical presentation and the main laboratory and imaging findings in a group of patients with PHPT diagnosed during the last 10 years. Materials and Methods: This was a retrospective cross-sectional study with data review from the last 10 years. Secondary causes for elevated PTH were excluded. The symptoms and signs of hypercalc...